SCHEMBL30350752

SCHEMBL30350752

NC(=O)Cc1cc(O)no1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.37
VHL P40337 1/20 0.37
CA2 P00918 1/20 0.36
ACACA Q13085 1/20 0.30
PLA2G10 O15496 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7423467 0.82 VHL (0.38) VHLCA2
SCHEMBL2402699 0.81 MMP2 (0.36)
SCHEMBL2829023 0.79 VHL (0.44) HTTVHL
SCHEMBL1698651 0.78 VHL (0.58) HTTVHL
SCHEMBL29776605 0.74 ALDH1A1 (0.44) HTTVHLCA2
SCHEMBL22724129 0.74 NNMT (0.43) HTTVHLPLA2G10
Muscimol SCHEMBL8680242 0.72 NOTUM (0.46)
Muscimol SCHEMBL352714 0.72
Muscimol SCHEMBL7440548 0.72
Muscimol SCHEMBL27765672 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107567443-B Biaryl derivatives as GPR120 agonists 株式会社LG化学 2023-04-28 CN disclosed
CN-115925679-A Biaryl derivatives as GPR120 agonists 株式会社LG化学 2023-04-07 CN disclosed