SCHEMBL303515

SCHEMBL303515

COC(C)c1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.56
ESR2 Q92731 11/20 0.56
PDCD1 Q15116 1/20 0.56
CD274 Q9NZQ7 1/20 0.56
LMNA P02545 2/20 0.44
CYP3A4 P08684 2/20 0.44
MAPT P10636 2/20 0.44
ALOX15 P16050 2/20 0.44
CYP1A2 P05177 1/20 0.44
PGR P06401 1/20 0.44
CHRM2 P08172 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
AR P10275 1/20 0.44
CYP2D6 P10635 1/20 0.44
CHRM1 P11229 1/20 0.44
CYP2C9 P11712 1/20 0.44
DRD1 P21728 1/20 0.44
TBXA2R P21731 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547833 0.93 AKR1C2 (0.51) ESR1ESR2PDCD1CD274LMNA
SCHEMBL1338710 0.87 AKR1C2 (0.42) ESR1ESR2PDCD1CD274TDP1
SCHEMBL17602077 0.86 ESR1 (0.43) ESR1ESR2PDCD1CD274LMNA
SCHEMBL17789898 0.84 ESR1 (0.50) ESR1ESR2PDCD1CD274LMNA
Methoxymethane SCHEMBL9478009 0.83 ESR1 (0.54) ESR1ESR2PDCD1CD274LMNA
SCHEMBL9479827 0.82 ESR1 (0.59) ESR1ESR2PDCD1CD274LMNA
SCHEMBL8750439 0.79 IDO1 (0.43) LMNACYP2D6CYP2C9PTGS1AKR1C2
SCHEMBL28950031 0.78 ESR1 (0.54) ESR1ESR2PDCD1CD274LMNA
SCHEMBL18905322 0.77 AKR1C2 (0.38) AKR1C2AKR1C1
SCHEMBL4518522 0.77 AKR1C2 (0.38) AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080589-A Preparation method of p-methoxyethylphenol 常州瑞明药业有限公司 2024-12-06 CN claimed
CN-119019231-A Preparation method of p-methoxyethylphenol 常州瑞明药业有限公司 2024-11-26 CN claimed
CN-117209653-B Three-chain-segment polymer dispersing agent, preparation method thereof and lithium manganese iron phosphate positive electrode slurry 江苏一特新材料有限责任公司 2024-01-02 CN claimed
CN-117209653-A Three-chain-segment polymer dispersing agent, preparation method thereof and lithium manganese iron phosphate positive electrode slurry 江苏一特新材料有限责任公司 2023-12-12 CN claimed
CN-114702372-B Method for preparing 4- (2-methoxyl) ethylphenol 台州市前进化工有限公司 2022-12-16 CN claimed
CN-115304500-A Method for synthesizing metoprolol impurity 北京康派森医药科技有限公司 2022-11-08 CN claimed
CN-114702372-A Method for preparing high-purity 4- (2-methoxy) ethylphenol 台州市前进化工有限公司 2022-07-05 CN claimed
CN-113150287-A Preparation method of cross-linkable fluorine-containing polyphosphazene 北京化工大学 2021-07-23 CN claimed
CN-111517967-A Method for synthesizing metoprolol succinate isomer impurity 山东齐都药业有限公司 2020-08-11 CN claimed
CN-111196783-A 2,4, 6-substituted pyrimidine derivatives containing acyl urea structure, and preparation method and application thereof 郑州大学 2020-05-26 CN claimed
WO-2010024841-A1 NEW PROPANOATES AND PROCESSES FOR PREPARING THE SAME DUPONT ELECTRONIC POLYMERS L.P. (US) 2010-03-04 WO claimed
US-20100047714-A1 New propanoates and processes for preparing the same U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2010-02-25 US claimed
US-20080214874-A1 Derivatized polyhydroxystyrenes with a novolak type structure and processes for preparing the same SHEEHAN MICHAEL T 2008-09-04 US claimed
US-7371800-B2 Derivatized novolak polyhydroxystyrene from hydroxyphenylmethylcarbinol DUPONT ELECTRONIC POLYMERS L.P. (US) 2008-05-13 US claimed
EP-1756191-A1 DERIVATIZED POLYHYDROXYSTYRENES WITH A NOVOLAK TYPE STRUCTURE AND PROCESSES FOR PREPARING THE SAME Dupont Electronic Polymers L.P. (US) 2007-02-28 EP claimed
WO-2006052380-A1 DERIVATIZED POLYHYDROXYSTRYRENE (DPHS)WITH A NOVOLAK TYPE STRUCTURE AND BLOCKED DPHS (BDPHS) AND PROCESSES FOR PREPARING THE SAME DUPONT ELECTRONIC POLYMERS L.P. (US) 2006-05-18 WO claimed
US-20060099531-A1 Derivatized polyhydroxystyrenes (DPHS) with a novolak type structure and blocked DPHS (BDPHS) and processes for preparing the same U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2006-05-11 US claimed
WO-2005113634-A1 DERIVATIZED POLYHYDROXYSTYRENES WITH A NOVOLAK TYPE STRUCTURE AND PROCESSES FOR PREPARING THE SAME DUPONT ELECTRONIC POLYMERS L.P. (US) 2005-12-01 WO claimed
US-20050250042-A1 Derivatized polyhydroxystyrenes with a novolak type structure and processes for preparing the same U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2005-11-10 US claimed
EP-0357310-B1 Process for producing substituted phenoxyethylamines and intermediates UBE INDUSTRIES (JP) 1994-03-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100047714-A1 New propanoates and processes for preparing the same HPD, HMBS, LDHB ESR1 1760/4885ESR2 2692/4885PDCD1 3014/4885
US-20080214874-A1 Derivatized polyhydroxystyrenes with a novolak type structure and processes for preparing the same VRK1, VRK2, CHKB ESR1 1023/4885ESR2 997/4885PDCD1 4464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.