Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 16/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.38 |
| ▸ | ATR | Q13535 | 3/20 | 0.37 |
| ▸ | ATRIP | Q8WXE1 | 3/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.36 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353085 | 1.00 | MTOR (0.39) | MTORPIK3CAPIK3R1ATRATRIP | |
| SCHEMBL25554625 | 1.00 | MTOR (0.39) | MTORPIK3CAPIK3R1ATRATRIP | |
| SCHEMBL25554628 | 1.00 | MTOR (0.39) | MTORPIK3CAPIK3R1ATRATRIP | |
| SCHEMBL30256596 | 0.89 | LMNA (0.42) | MTORPIK3CAPIK3CDPIK3CBPIK3C3 | |
| SCHEMBL23949247 | 0.89 | LMNA (0.42) | MTORPIK3CAPIK3CDPIK3CBPIK3C3 | |
| SCHEMBL30256947 | 0.86 | PIK3CA (0.35) | MTORPIK3CAPIK3R1PIK3CGRICTOR | |
| SCHEMBL25554572 | 0.86 | PIK3CA (0.35) | MTORPIK3CAPIK3R1PIK3CGRICTOR | |
| SCHEMBL30353124 | 0.85 | ALDH1A1 (0.41) | MTORPIK3CA | |
| SCHEMBL25554226 | 0.85 | ALDH1A1 (0.41) | MTORPIK3CA | |
| SCHEMBL25555242 | 0.84 | CYP11B2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |