Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353071 | 0.82 | TBXAS1 (0.36) | TBXAS1FNTAFNTBPGGT1BHRH3 | |
| SCHEMBL30353122 | 0.79 | TBXAS1 (0.38) | TBXAS1FNTAFNTBPGGT1BHRH3 | |
| SCHEMBL30353077 | 0.76 | EGLN2 (0.40) | TBXAS1FNTAFNTBPGGT1BMGLL | |
| SCHEMBL509344 | 0.66 | KCNH2 (0.41) | TBXAS1FNTAFNTBPGGT1BEPAS1 | |
| SCHEMBL8379001 | 0.65 | PDE4A (0.54) | TBXAS1EPAS1PDE4APDE4BPDE4C | |
| SCHEMBL27839327 | 0.64 | PDE4A (0.53) | TBXAS1EPAS1PDE4APDE4BPDE4C | |
| SCHEMBL23949264 | 0.63 | — | — | |
| SCHEMBL12750184 | 0.63 | TBXAS1 (0.55) | TBXAS1ICMT | |
| SCHEMBL921758 | 0.63 | LTA4H (0.50) | TBXAS1PPARGPDE4APDE4BPDE4C | |
| SCHEMBL923347 | 0.63 | LTA4H (0.59) | TBXAS1PPARGPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |