Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353122 | 0.82 | TBXAS1 (0.38) | TBXAS1MGLLFNTAFNTBPGGT1B | |
| SCHEMBL30353093 | 0.76 | TBXAS1 (0.38) | TBXAS1MGLLFNTAFNTBPGGT1B | |
| SCHEMBL30353071 | 0.76 | TBXAS1 (0.36) | TBXAS1MGLLFNTAFNTBPGGT1B | |
| SCHEMBL25058086 | 0.68 | EGLN2 (0.31) | EGLN2 | |
| SCHEMBL1848360 | 0.65 | SLC6A2 (0.57) | TBXAS1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8379001 | 0.64 | PDE4A (0.54) | TBXAS1SLC6A2SLC6A4SLC6A3GRIA2 | |
| SCHEMBL3605627 | 0.63 | MET (0.52) | DRD2DRD3MGLLSLC6A2SLC6A4 | |
| SCHEMBL3601894 | 0.62 | DRD2 (0.50) | TBXAS1DRD2DRD3MGLLSLC6A2 | |
| SCHEMBL509344 | 0.62 | KCNH2 (0.41) | TBXAS1FNTAFNTBPGGT1BGRIA2 | |
| SCHEMBL27839327 | 0.62 | PDE4A (0.53) | TBXAS1SLC6A2SLC6A4SLC6A3GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |