Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CDC25B | P30305 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435084 | 1.00 | KMT2A (0.59) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL3092388 | 0.86 | KMT2A (0.63) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL8672958 | 0.86 | RAB9A (0.60) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL10145068 | 0.84 | RAB9A (0.61) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL24077536 | 0.83 | KMT2A (0.57) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL8683968 | 0.83 | NAMPT (0.65) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL30807828 | 0.83 | RAB9A (0.60) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL24077783 | 0.83 | RAB9A (0.60) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL10106419 | 0.83 | MAPT (0.65) | KMT2AALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL11158358 | 0.83 | MAPT (0.58) | KMT2AALDH1A1TSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161917-A1 | GRK2 INHIBITORS AND USES THEREOF | Cygnal Therapeutics, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |