Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134016 | 0.87 | EGFR (0.57) | RAB9AEGFRMAPK1HSD17B10POLB | |
| SCHEMBL30353836 | 0.86 | KMT2A (0.59) | RAB9AMAPK1HSD17B10POLBALDH1A1 | |
| SCHEMBL14435084 | 0.86 | KMT2A (0.59) | RAB9AMAPK1HSD17B10POLBALDH1A1 | |
| SCHEMBL8569963 | 0.85 | RAB9A (0.58) | RAB9AEGFRMAPK1HSD17B10POLB | |
| SCHEMBL18552696 | 0.84 | POLB (0.68) | RAB9AEGFRMAPK1HSD17B10POLB | |
| SCHEMBL4604254 | 0.84 | EGFR (0.54) | RAB9AEGFRMAPK1HSD17B10POLB | |
| SCHEMBL25174147 | 0.83 | RAB9A (0.59) | RAB9AEGFRMAPK1HSD17B10POLB | |
| SCHEMBL30445248 | 0.83 | RAB9A (0.59) | RAB9AEGFRMAPK1HSD17B10POLB | |
| SCHEMBL2635975 | 0.83 | EGFR (0.53) | RAB9AEGFRMAPK1HSD17B10POLB | |
| SCHEMBL4605992 | 0.83 | LOXL2 (0.55) | RAB9AEGFRMAPK1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022182845-A1 | MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2022-09-01 | — | — | WO | disclosed |
| US-5783689-A | Antibacterial and antifungal nucleosides | UNIVERSITY OF NOTRE DAME (US) | 1998-07-21 | — | — | US | disclosed |