Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | PPIA | P62937 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24077783 | 1.00 | RAB9A (0.60) | RAB9AMAPTPKMPPIANPC1 | |
| SCHEMBL7336552 | 0.86 | PKM (0.67) | RAB9AMAPTPKMNPC1KMT2A | |
| SCHEMBL7134779 | 0.85 | MAPT (0.65) | RAB9AMAPTPKMPPIANPC1 | |
| SCHEMBL10106419 | 0.83 | MAPT (0.65) | RAB9AMAPTPKMNPC1POLB | |
| SCHEMBL14435084 | 0.83 | KMT2A (0.59) | RAB9AMAPTPKMNPC1POLB | |
| SCHEMBL30353836 | 0.83 | KMT2A (0.59) | RAB9AMAPTPKMNPC1POLB | |
| SCHEMBL7140628 | 0.82 | RAB9A (0.52) | RAB9AMAPTPKMPPIANPC1 | |
| SCHEMBL11365574 | 0.81 | KMT2A (0.52) | RAB9AMAPTPKMNPC1POLB | |
| SCHEMBL11456258 | 0.81 | L3MBTL1 (0.56) | RAB9AMAPTPKMPOLBKMT2A | |
| SCHEMBL11323179 | 0.80 | AKR1C3 (0.61) | RAB9ANPC1POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580831-A | GRK2 inhibitors and uses thereof | 索纳塔治疗公司 | 2024-02-20 | — | — | CN | disclosed |