SCHEMBL30356271

SCHEMBL30356271

COc1cc(O)ccc1NC(N)=S

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
HPGD P15428 1/20 0.51
MAOB P27338 1/20 0.48
EPHX1 P07099 3/20 0.47
GAA P10253 1/20 0.45
KMT2A Q03164 2/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
TNIK Q9UKE5 1/20 0.42
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11883401 0.86 PYGL (0.46) ALDH1A1HPGDMAOBGAAKMT2A
SCHEMBL2590631 0.83 ALDH1A1 (0.75) ALDH1A1HPGDGAAKMT2A
SCHEMBL30356244 0.83 ALDH1A1 (0.75) ALDH1A1HPGDGAAKMT2A
SCHEMBL6114130 0.79 PYGL (0.52) ALDH1A1HPGDEPHX1KMT2AKDM4E
SCHEMBL28047546 0.79 ALDH1A1 (0.47) ALDH1A1HPGDEPHX1GAAKMT2A
SCHEMBL17085567 0.79 ALDH1A1 (0.51) ALDH1A1HPGDEPHX1GAAKMT2A
SCHEMBL29557119 0.78 MAOB (0.55) ALDH1A1HPGDMAOBKMT2AESR1
SCHEMBL30810230 0.78 ALDH1A1 (0.46) ALDH1A1HPGDEPHX1GAAKMT2A
SCHEMBL7938081 0.77 MAOB (0.59) ALDH1A1HPGDMAOBGAAKMT2A
SCHEMBL14782205 0.77 HSD17B1 (0.57) ALDH1A1MAOBEPHX1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250186309-A1 DENTAL CURABLE COMPOSITION AND DENTAL KIT KURARAY NORITAKE DENTAL INC. (JP) 2025-06-12 US disclosed
EP-4413968-A1 CURABLE DENTAL COMPOSITION AND DENTAL KIT Kuraray Noritake Dental Inc. (JP) 2024-08-14 EP disclosed
WO-2023058773-A1 CURABLE DENTAL COMPOSITION AND DENTAL KIT クラレノリタケデンタル株式会社 2023-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186309-A1 DENTAL CURABLE COMPOSITION AND DENTAL KIT KIT, DNMT3L, CDK6 ALDH1A1 2887/4885HPGD 3943/4885MAOB 4158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.