Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15152595 | 1.00 | ACACB (0.33) | ACACBMMP1MMP2MMP3GPR88 | |
| SCHEMBL15152594 | 1.00 | ACACB (0.33) | ACACBMMP1MMP2MMP3GPR88 | |
| SCHEMBL13601106 | 0.83 | CA1 (0.45) | — | |
| SCHEMBL14496961 | 0.83 | CA1 (0.45) | — | |
| SCHEMBL13496155 | 0.83 | CA1 (0.45) | — | |
| SCHEMBL14593178 | 0.81 | MTNR1A (0.35) | ACACB | |
| SCHEMBL15152590 | 0.81 | GPR88 (0.33) | MMP1MMP2MMP3GPR88 | |
| SCHEMBL27638974 | 0.81 | GPR88 (0.33) | MMP1MMP2MMP3GPR88 | |
| SCHEMBL16649611 | 0.81 | GPR88 (0.33) | MMP1MMP2MMP3GPR88 | |
| SCHEMBL16751311 | 0.77 | TAS1R3 (0.32) | GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49556-E1 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-20230116233-A1 | Compounds And Compositions As Protein Kinase Inhibitors | ARRAY BIOPHARMA INC (US) | 2023-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230116233-A1 | Compounds And Compositions As Protein Kinase Inhibitors | BRAF, RAF1, ARAF | ACACB 799/4885MMP1 4164/4885MMP2 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.