Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25195292 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL304349 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL30255032 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL18297654 | 0.80 | ERN1 (0.35) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL15240397 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL29956118 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL5212066 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL3649684 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL4322219 | 0.77 | ERN1 (0.38) | ALDH1A1MEN1KMT2ATDP1CCR1 | |
| SCHEMBL199582 | 0.77 | CCR1 (0.32) | ALDH1A1MEN1KMT2ATDP1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185579-A1 | INHIBITORS OF RHO-ASSOCIATED COILED-COIL KINASE | Angion Biomedica Corp. (US) | 2023-05-31 | — | — | EP | disclosed |