Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30255032 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL5212066 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL29956118 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL15240397 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL30356708 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL25195292 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL29952613 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL1863142 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL3649684 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL529516 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TDP1MEN1KMT2ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688748-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2026-02-11 | — | — | EP | disclosed |
| US-20260008774-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS INC (US) | 2026-01-08 | — | — | US | disclosed |
| US-12448369-B2 | Quinolinone amide compounds and uses thereof | EDGEWISE THERAPEUTICS, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| US-20250163078-A1 | IMIDAZOPYRIDAZINE DERIVATIVE, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2025-05-22 | — | — | US | disclosed |
| EP-4548974-A2 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2025-05-07 | — | — | EP | disclosed |
| EP-3853218-B1 | SOMATOSTATIN MODULATORS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20250026740-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. | 2025-01-23 | — | — | US | disclosed |
| EP-4484433-A1 | IMIDAZOPYRIDAZINE DERIVATIVE, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2025-01-01 | — | — | EP | disclosed |
| US-20240408247-A1 | NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF | RADIONETICS ONCOLOGY, INC. | 2024-12-12 | — | — | US | disclosed |
| CN-115151550-B | External nucleotide pyrophosphatase/phosphodiesterase 1 (ENPP 1) modulators and uses thereof | 桑福德·伯纳姆·普雷比医学发现研究所 | 2024-11-22 | — | — | CN | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |
| US-7074742-B2 | Pyridinyl amides and imides for use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-07-11 | — | — | US | disclosed |
| US-20050009889-A1 | Synergistic fungicide compositions containing at least one n-(2-pyridinyl) 1-3-pyridinecarboxamide derivative and one or more further fungicides useful for controlling fungal plant diseases | E.I. DU PONE DE NEMOURS AND COMPANY | 2005-01-13 | — | — | US | disclosed |
| US-20040044040-A1 | Pyridinyl amides and imides for use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-03-04 | — | — | US | disclosed |
| WO-2003079787-A9 | SYNERGISTIC FUNGICIDE COMPOSITIONS CONTAINING AT LEAST ONE N-`(2-PYRIDINYL)METHYL!-3-PYRIDINECARBOXAMIDE DERIVATIVE AND ONE OR MORE FURTHER FUNGICIDES USEFUL FOR CONTROLLING FUNGAL PLANT DISEASES | DU PONT (US) | 2004-02-12 | — | — | WO | disclosed |
| EP-1322614-A2 | PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES | E. I. du Pont de Nemours and Company (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002022583-A2 | PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
| EP-0702003-B1 | Process for preparing 2-halogenpyridinaldehydes | BAYER AG (DE) | 1998-06-17 | — | — | EP | disclosed |
| US-5708180-A | CYCLIZATION OF UNSATURATED NITRILE, AMIDE OR OXIME | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| EP-0702003-A2 | Process for preparing 2-halogenpyridinaldehydes and new 2-halogenpyridinaldehydes | BAYER AG (DE) | 1996-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163078-A1 | IMIDAZOPYRIDAZINE DERIVATIVE, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | CYP4A11, CYP4F11, SLC6A11 | ALDH1A1 437/4885TDP1 918/4885MEN1 3177/4885 |
| US-12448369-B2 | Quinolinone amide compounds and uses thereof | TNNI3, TNNT2, COQ8A | ALDH1A1 461/4885TDP1 1600/4885MEN1 3354/4885 |
| US-20050009889-A1 | Synergistic fungicide compositions containing at least one n-(2-pyridinyl) 1-3-pyridinecarboxamide derivative and one or more further fungicides useful for controlling fungal plant diseases | CYC1, ME3, CYP11B1 | ALDH1A1 1301/4885TDP1 1443/4885MEN1 2003/4885 |
| US-20240408247-A1 | NON-PEPTIDE TARGETED THERAPEUTICS AND USES THEREOF | GRPR, SCTR, NPSR1 | ALDH1A1 4162/4885TDP1 4318/4885MEN1 1446/4885 |
| US-20040044040-A1 | Pyridinyl amides and imides for use as fungicides | CBR1, CBR3, AOC3 | ALDH1A1 1067/4885TDP1 2933/4885MEN1 2225/4885 |
| US-20250026740-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | TNNI3, TNNT2, COQ8A | ALDH1A1 461/4885TDP1 1600/4885MEN1 3354/4885 |
| US-20260008774-A1 | QUINOLINONE AMIDE COMPOUNDS AND USES THEREOF | TNNT2, TNNI3, TNNC1 | ALDH1A1 1031/4885TDP1 2708/4885MEN1 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.