Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.44 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.43 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13363749 | 1.00 | SMYD3 (0.47) | SMYD3HPGDSLC6A5HDAC4HDAC6 | |
| SCHEMBL13175828 | 0.87 | SMYD3 (0.55) | SMYD3HPGD | |
| SCHEMBL3545889 | 0.86 | NPC1 (0.48) | SMYD3HPGDSLC6A5HDAC4HDAC6 | |
| SCHEMBL14452338 | 0.86 | HRH3 (0.58) | SMYD3ALDH1A1ROCK2DRD4 | |
| SCHEMBL3543621 | 0.85 | HDAC6 (0.52) | SMYD3HPGDSLC6A5HDAC4HDAC6 | |
| SCHEMBL1559555 | 0.85 | KMT2A (0.49) | SMYD3SLC6A5 | |
| SCHEMBL4052654 | 0.84 | ACSS2 (0.47) | SMYD3HPGDSLC6A5HDAC4HDAC6 | |
| SCHEMBL14146060 | 0.84 | KMT2A (0.49) | SMYD3HPGDSLC6A5HDAC4HDAC6 | |
| SCHEMBL13808664 | 0.83 | ROCK2 (0.46) | SMYD3HPGDSLC6A5HDAC4HDAC6 | |
| SCHEMBL738237 | 0.83 | HTR4 (0.53) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059582-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2023-04-13 | — | — | WO | disclosed |