Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4802524 | 0.83 | TSPO (0.48) | KMT2AMAPTL3MBTL1SMN1; SMN2TSPO | |
| SCHEMBL3038709 | 0.80 | RXFP1 (0.40) | RXFP1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL3041673 | 0.79 | KMT2A (0.39) | RXFP1KMT2AGAAMAPTSMN1; SMN2 | |
| SCHEMBL3035741 | 0.78 | KMT2A (0.46) | RXFP1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL28008494 | 0.76 | ALDH1A1 (0.41) | KMT2AMAPTL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL29118727 | 0.74 | NPC1 (0.43) | RXFP1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL29118672 | 0.73 | ADORA2A (0.51) | MAPTL3MBTL1SMN1; SMN2CYP3A4TSHR | |
| SCHEMBL3039772 | 0.71 | TSPO (0.52) | RXFP1KMT2AL3MBTL1TSPOMEN1 | |
| SCHEMBL3041620 | 0.71 | TSPO (0.52) | RXFP1KMT2AL3MBTL1TSPOMEN1 | |
| SCHEMBL8474538 | 0.70 | TSPO (0.48) | MAPTL3MBTL1TSPOCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110064662-A1 | KIT FOR PRODUCING MOLECULAR PROBE FOR PET SCREENING FOR DRUG DISCOVERY | RIKEN (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20110064662-A1 | KIT FOR PRODUCING MOLECULAR PROBE FOR PET SCREENING FOR DRUG DISCOVERY | RIKEN (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20110064662-A1 | KIT FOR PRODUCING MOLECULAR PROBE FOR PET SCREENING FOR DRUG DISCOVERY | RIKEN (JP) | 2011-03-17 | — | — | US | disclosed |
| EP-2228363-A1 | KIT FOR USE IN PRODUCTION OF MOLECULAR PROBE FOR PET DRUG SCREENING | Riken (JP) | 2010-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110064662-A1 | KIT FOR PRODUCING MOLECULAR PROBE FOR PET SCREENING FOR DRUG DISCOVERY | KIT, TPX2, RUNX1 | RXFP1 540/4885KMT2A 2122/4885GAA 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.