Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 2/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22821573 | 0.86 | HPGD (0.48) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL3400892 | 0.84 | ALDH1A1 (0.49) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL12856521 | 0.83 | HPGD (0.46) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL31226138 | 0.83 | KDM4E (0.48) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL22640849 | 0.83 | KDM4E (0.48) | HPGDKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL24227433 | 0.83 | PRMT5 (0.57) | HPGDKDM4EALDH1A1RAB9AKMT2A | |
| SCHEMBL26054498 | 0.83 | ALDH1A1 (0.48) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL20329603 | 0.83 | ALDH1A1 (0.48) | HPGDKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL905517 | 0.83 | KDM4E (0.48) | HPGDKDM4EALDH1A1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL1116045 | 0.81 | KDM4E (0.47) | HPGDKDM4EALDH1A1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960010-B | Preparation of aniline compounds | 上海慧聚药业有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-115960010-A | Preparation of aniline compounds | 上海慧聚药业有限公司 | 2023-04-14 | — | — | CN | disclosed |