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SCHEMBL3400892

SCHEMBL3400892

O=C(NCC(O)CO)c1cc(O)cc(C(=O)NCC(O)CO)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.49
▸ KDM4E B2RXH2 2/20 0.49
▸ HPGD P15428 1/20 0.49
▸ HSD17B10 Q99714 2/20 0.42
▸ GAA P10253 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ CA2 P00918 1/20 0.41
▸ BACE1 P56817 1/20 0.39
▸ EGFR P00533 1/20 0.38
▸ SRC P12931 1/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ ACSS2 Q9NR19 2/20 0.37
▸ NQO2 P16083 1/20 0.37
▸ LOX P28300 1/20 0.37
▸ LOXL2 Q9Y4K0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14793018 0.95 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL29234296 0.92 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL30945842 0.92 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL14777914 0.91 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL26054346 0.85 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL905517 0.84 KDM4E (0.48) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL31226138 0.84 KDM4E (0.48) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL22821573 0.84 HPGD (0.48) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL22640849 0.84 KDM4E (0.48) ALDH1A1KDM4EHPGDHSD17B10GAA
SCHEMBL30358366 0.84 HPGD (0.48) ALDH1A1KDM4EHPGDHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12269790-B1 Process for the preparation of 2,4,6-triiodophenol derivatives BRACCO IMAGING S.P.A. (IT) 2025-04-08 — — US claimed
US-20250109094-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES BRACCO IMAGING S.P.A. (IT) 2025-04-03 — — US claimed
WO-2023209165-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES BRACCO IMAGING SPA (IT) 2023-11-02 — — WO claimed
EP-1133466-B1 A PROCESS FOR THE PREPARATION OF N,N'-BIS 2, 3-DIHYDROXYPROPYL] -5-[(HYDROXYACETYL) METHYLAMINO]-2, 4,6-TRIIODO-1, 3-BENZENEDI CARBOXAMIDE BRACCO INT BV (NL) 2003-08-20 — — EP claimed
US-6420603-B1 ESTERIFICATION OF 5-HYDROXYISOPHTHALIC ACID, AMIDATION WITH ISOSERINOL, IODINATION AND ALKYLATION BRACCO INTERNATIONAL B.V. (NL) 2002-07-16 — — US claimed
US-12269790-B1 Process for the preparation of 2,4,6-triiodophenol derivatives BRACCO IMAGING S.P.A. (IT) 2025-04-08 — — US disclosed
US-20250109094-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES BRACCO IMAGING S.P.A. (IT) 2025-04-03 — — US disclosed
CN-119095823-A Process for preparing 2,4, 6-triiodophenol derivatives 伯拉考成像股份公司 2024-12-06 — — CN disclosed
WO-2023209165-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES BRACCO IMAGING SPA (IT) 2023-11-02 — — WO disclosed
WO-2023209165-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES BRACCO IMAGING SPA (IT) 2023-11-02 — — WO disclosed
US-20220024857-A1 METHOD FOR PREPARING CONTRAST AGENT IOMEPROL UK CHEMIPHARM CO., LTD (KR) 2022-01-27 — — US disclosed
EP-2254850-B1 PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS BRACCO IMAGING SPA (IT) 2016-06-22 — — EP disclosed
WO-2009103666-A2 PROCESS FOR THE IODINATION OF AROMATIC COMPOUNDS BRACCO IMAGING SPA (IT) 2009-08-27 — — WO disclosed
EP-2093206-A1 Process for the iodination of aromatic compounds BRACCO IMAGING S.p.A. (IT) 2009-08-26 — — EP disclosed
EP-1133466-B1 A PROCESS FOR THE PREPARATION OF N,N'-BIS 2, 3-DIHYDROXYPROPYL] -5-[(HYDROXYACETYL) METHYLAMINO]-2, 4,6-TRIIODO-1, 3-BENZENEDI CARBOXAMIDE BRACCO INT BV (NL) 2003-08-20 — — EP disclosed
US-6420603-B1 ESTERIFICATION OF 5-HYDROXYISOPHTHALIC ACID, AMIDATION WITH ISOSERINOL, IODINATION AND ALKYLATION BRACCO INTERNATIONAL B.V. (NL) 2002-07-16 — — US disclosed
US-5700448-A Use of persistent free-radicals in magnetic resonance imaging NYCOMED IMAGING AS (NO) 1997-12-23 — — US disclosed
EP-0662004-A1 USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING Nycomed Innovation AB (SE) 1995-07-12 — — EP disclosed
WO-1993002710-A2 USE OF PERSISTENT FREE RADICALS IN MAGNETIC RESONANCE IMAGING NYCOMED INNOVATION AB (SE) 1993-02-18 — — WO disclosed
WO-1993002711-A1 USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING NYCOMED INNOVATION AB (SE) 1993-02-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220024857-A1 METHOD FOR PREPARING CONTRAST AGENT IOMEPROL PPIP5K2, SLC5A11, INMT ALDH1A1 4045/4885KDM4E 1910/4885HPGD 2968/4885
US-20250109094-A1 PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOPHENOL DERIVATIVES TPO, IPO4, CYP4F2 ALDH1A1 1627/4885KDM4E 2220/4885HPGD 1604/4885
US-12269790-B1 Process for the preparation of 2,4,6-triiodophenol derivatives TPO, IPO4, CYP4F2 ALDH1A1 1627/4885KDM4E 2220/4885HPGD 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.