Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30359001 | 0.87 | PIN1 (0.44) | LMNAHTTKDM4EHSD11B1KMT2A | |
| SCHEMBL30359139 | 0.83 | PIK3CD (0.47) | HTTMGLLCYP2C9CYP2C19MAPK14 | |
| SCHEMBL30359097 | 0.80 | MEN1 (0.45) | LMNAHTTMGLLKDM4ECYP2C9 | |
| SCHEMBL6276557 | 0.76 | HTT (0.58) | LMNAHTTCYP2C9CYP2C19MAPK14 | |
| SCHEMBL30359092 | 0.76 | HTT (0.58) | LMNAHTTMGLLKDM4ECYP2C9 | |
| SCHEMBL30359168 | 0.75 | ALDH1A1 (0.49) | LMNAMGLLKDM4EHSD11B1KMT2A | |
| SCHEMBL30359065 | 0.75 | HCRTR1 (0.43) | MGLLHSD11B1KMT2AALDH1A1HCRTR2 | |
| SCHEMBL30790460 | 0.75 | SLC6A4 (0.43) | LMNAMGLLTSHRHCRTR2HCRTR1 | |
| SCHEMBL30359048 | 0.74 | KCNK3 (0.45) | MGLL | |
| SCHEMBL10293549 | 0.74 | LMNA (0.50) | LMNAHTTMGLLKDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |