SCHEMBL30359196

SCHEMBL30359196

CC(C)N(C)C(=O)N1C2CCC1CNC2

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 1/20 0.32
KCNK9 Q9NPC2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25423652 0.85 CHRNB2 (0.31) KCNK3KCNK9
SCHEMBL29432747 0.84
SCHEMBL30359038 0.83 MAPK1 (0.34)
SCHEMBL28653925 0.82 GRM5 (0.39)
SCHEMBL26204857 0.75 ALDH1A1 (0.43)
SCHEMBL28997119 0.74 HTR1A (0.39) KCNK3KCNK9
SCHEMBL25895305 0.74 CHRNB2 (0.43) KCNK3KCNK9
SCHEMBL742194 0.71 CHRNB2 (0.45)
SCHEMBL2302714 0.71 CHRNB2 (0.45)
SCHEMBL30358994 0.70 CHRNB2 (0.42) KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116057057-A Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea 拜耳公司 2023-05-02 CN disclosed