Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84864 | 0.94 | NPSR1 (0.50) | NPSR1FLT3NPC1HPGDALDH1A1 | |
| SCHEMBL17102638 | 0.79 | NPC1 (0.41) | NPSR1FLT3NPC1HPGDALDH1A1 | |
| SCHEMBL2140506 | 0.77 | NPSR1 (0.46) | NPSR1FLT3NPC1HPGDALDH1A1 | |
| SCHEMBL30359488 | 0.77 | NPSR1 (0.39) | NPSR1FLT3NPC1HPGDALDH1A1 | |
| SCHEMBL24349591 | 0.73 | SSTR4 (0.54) | NPSR1FLT3NPC1HPGDALDH1A1 | |
| SCHEMBL10146037 | 0.73 | GPR84 (0.49) | NPSR1FLT3ALDH1A1ADORA3GPR84 | |
| SCHEMBL10518268 | 0.72 | ALDH1A1 (0.56) | NPSR1FLT3NPC1HPGDALDH1A1 | |
| SCHEMBL28269101 | 0.72 | SMN1; SMN2 (0.59) | NPC1HPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9913664 | 0.70 | EPHB3 (0.62) | NPC1HPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL335455 | 0.69 | PKM (0.51) | NPSR1FLT3NPC1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788362-B1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-0788362-A1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1993024131-A1 | PHOSPONOCARBOXYLATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |