Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 9/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17980278 | 1.00 | CA2 (0.39) | CA2MPOSLC6A4TAAR1GABRA1 | |
| SCHEMBL28521050 | 0.88 | TAAR1 (0.39) | MPOSLC6A4TAAR1GABRA1GABRB2 | |
| SCHEMBL4610914 | 0.80 | CA2 (0.41) | CA2MPOSLC6A4TAAR1 | |
| SCHEMBL595715 | 0.79 | GPR84 (0.42) | MPOSLC6A4TAAR1GABRA1GABRB2 | |
| SCHEMBL31145066 | 0.79 | GPR84 (0.42) | MPOSLC6A4TAAR1GABRA1GABRB2 | |
| SCHEMBL80668 | 0.79 | TAAR1 (0.58) | CA2MPOSLC6A4TAAR1AOC3 | |
| SCHEMBL31069259 | 0.79 | TAAR1 (0.58) | CA2MPOSLC6A4TAAR1AOC3 | |
| SCHEMBL28306347 | 0.79 | LIPG (0.44) | GABRA1GABRB2 | |
| SCHEMBL31627734 | 0.78 | TAAR1 (0.61) | MPOSLC6A4TAAR1GABRA1GABRB2 | |
| SCHEMBL28794719 | 0.78 | TAAR1 (0.40) | MPOSLC6A4TAAR1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4464317-A2 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | Sumitomo Pharma America, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| EP-3494119-B1 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SUMITOMO PHARMA AMERICA INC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-111925360-B | 1-heterocyclylisochromanyl compounds and analogs for the treatment of CNS disorders | 赛诺维信制药公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-116514761-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116283877-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |