Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.57 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812997 | 1.00 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL30360710 | 0.83 | DRD1 (0.60) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL19812914 | 0.83 | DRD1 (0.60) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL32670712 | 0.83 | DRD1 (0.60) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL19813088 | 0.83 | DRD1 (0.60) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL19812912 | 0.83 | DRD1 (0.60) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL30360712 | 0.83 | DRD1 (0.60) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL19812847 | 0.81 | ADRA1A (0.41) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL19821182 | 0.80 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL10925316 | 0.79 | ADRA2A (0.71) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4464317-A2 | COMPOUNDS AND COMPOSITIONS AND USES THEREOF | Sumitomo Pharma America, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| CN-116514761-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116283877-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |