Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 4/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812914 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2AHTR2B | |
| SCHEMBL19812912 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2AHTR2B | |
| SCHEMBL32670712 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2AHTR2B | |
| SCHEMBL30360710 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2AHTR2B | |
| SCHEMBL19813088 | 1.00 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2AHTR2B | |
| SCHEMBL15319616 | 0.84 | DRD1 (0.42) | DRD1HTR2CHTR2AHTR2BADRA2A | |
| SCHEMBL30360702 | 0.83 | ADRA2A (0.57) | DRD1KEAP1HTR2CHTR2AHTR2B | |
| SCHEMBL19812997 | 0.83 | ADRA2A (0.57) | DRD1KEAP1HTR2CHTR2AHTR2B | |
| SCHEMBL19813036 | 0.81 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2AHTR2B | |
| SCHEMBL19812863 | 0.81 | DRD1 (0.60) | DRD1KEAP1HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |