Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657647 | 1.00 | CYP3A4 (0.42) | CYP3A4HIF1AMEN1HPGDKMT2A | |
| SCHEMBL924319 | 0.88 | HIF1A (0.39) | CYP3A4HIF1AMEN1HPGDKMT2A | |
| SCHEMBL29381205 | 0.88 | HIF1A (0.39) | CYP3A4HIF1AMEN1HPGDKMT2A | |
| SCHEMBL2560634 | 0.87 | NOS3 (0.44) | CYP3A4HIF1AMEN1HPGDKMT2A | |
| SCHEMBL3634811 | 0.83 | PYCR1 (0.44) | CYP3A4HIF1AMEN1HPGDKMT2A | |
| SCHEMBL500015 | 0.83 | CYP3A4 (0.45) | CYP3A4HIF1AMEN1HPGDKMT2A | |
| SCHEMBL12713145 | 0.81 | NOS3 (0.41) | CYP3A4HIF1AMEN1HPGDKMT2A | |
| SCHEMBL4967338 | 0.81 | NOS3 (0.41) | CYP3A4HIF1AMEN1HPGDKMT2A | |
| SCHEMBL16268636 | 0.79 | TAAR1 (0.52) | CYP3A4HIF1AMEN1HPGDKMT2A | |
| SCHEMBL29960836 | 0.79 | TAAR1 (0.52) | CYP3A4HIF1AMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514761-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116283877-A | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110088107-B | Compounds, compositions and uses thereof | 赛诺维信制药公司 | 2023-04-14 | — | — | CN | disclosed |