SCHEMBL30360771

SCHEMBL30360771

CC(C)(C)c1ccc(Sc2ccc(C#N)c(C#N)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.64
MAOA P21397 10/20 0.64
DHFR P00374 1/20 0.48
MCL1 Q07820 2/20 0.47
KIF11 P52732 1/20 0.42
AR P10275 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21878993 1.00 MAOB (0.64) MAOBMAOADHFRMCL1KIF11
SCHEMBL13907659 0.83 MAOB (0.80) MAOBMAOAMCL1AR
SCHEMBL30360762 0.80 MAOB (0.70) MAOBMAOAMCL1AR
SCHEMBL20511089 0.80 MAOB (0.70) MAOBMAOAMCL1AR
SCHEMBL497451 0.79 KIF11 (0.47) MAOBMAOAKIF11AR
SCHEMBL30566936 0.79 KIF11 (0.47) MAOBMAOAKIF11AR
SCHEMBL523640 0.78 MAOB (1.00) MAOBMAOAMCL1AR
SCHEMBL2271509 0.77 TSHR (0.52) DHFRKIF11
SCHEMBL22749185 0.77 MAOB (0.70) MAOBMAOAMCL1AR
SCHEMBL12949048 0.77 MAOB (1.00) MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110461814-B Resin blends, prepregs and articles containing a phthalonitrile reactive diluent and a bisphthalonitrile resin 3M创新有限公司 2023-04-14 CN disclosed