SCHEMBL30360775

SCHEMBL30360775

c1ccc2c(c1)CCc1ccccc1O2

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.70
MAOB P27338 2/20 0.70
GAA P10253 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TSHR P16473 1/20 0.43
ALOX5 P09917 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.41
ITGB2 P05107 1/20 0.41
ICAM1 P05362 1/20 0.41
ITGAL P20701 1/20 0.41
SETD7 Q8WTS6 1/20 0.41
CES1 P23141 1/20 0.40
OXTR P30559 1/20 0.39
ORAI1 Q96D31 1/20 0.39
ORAI2 Q96SN7 1/20 0.39
ORAI3 Q9BRQ5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL971330 1.00 MAOA (0.70) MAOAMAOBGAANPSR1NPC1
SCHEMBL4500547 0.89 MAOA (0.64) MAOAMAOBGAANPSR1NPC1
SCHEMBL7295118 0.83 MAOA (0.50) MAOAMAOBGAANPSR1NPC1
SCHEMBL13950592 0.83 MAOA (0.50) MAOAMAOBGAANPSR1NPC1
SCHEMBL29586724 0.83 MAOA (0.50) MAOAMAOBGAANPSR1NPC1
SCHEMBL11096945 0.83 HTR2C (0.65) MAOAMAOBGAANPSR1NPC1
SCHEMBL5733780 0.83 MAOA (0.50) MAOAMAOBGAANPSR1NPC1
SCHEMBL12773597 0.83 MAOA (0.50) MAOAMAOBGAANPSR1NPC1
Dihydrocoumarin SCHEMBL28795 0.83 MAOB (0.50) MAOAMAOBGAANPSR1NPC1
Dihydrocoumarin SCHEMBL17629427 0.83 MAOB (0.50) MAOAMAOBGAANPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112876498-B Polycyclic aromatic compound and organic electroluminescent element containing same 北京八亿时空液晶科技股份有限公司 2023-04-18 CN disclosed