Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.32 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30361787 | 0.80 | ADORA1 (0.36) | ADORA1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30362058 | 0.77 | S1PR1 (0.40) | ADORA1EGFRFAAH | |
| SCHEMBL30361987 | 0.77 | S1PR1 (0.44) | ADORA1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30361895 | 0.77 | PDE10A (0.40) | — | |
| SCHEMBL26104108 | 0.76 | EGFR (0.49) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL30361897 | 0.76 | PTGS2 (0.38) | ADORA1MAPTFAAHDPP4ALDH1A1 | |
| SCHEMBL30362000 | 0.74 | PTGS2 (0.35) | ADORA1EGFRFAAH | |
| SCHEMBL30361925 | 0.74 | S1PR1 (0.37) | ADORA1EGFRFAAH | |
| SCHEMBL30362140 | 0.74 | CSNK1D (0.35) | ADORA1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30361907 | 0.72 | CSNK1D (0.35) | ADORA1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076849-A1 | INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR | ORIC PHARMACEUTICALS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |