SCHEMBL30362164

SCHEMBL30362164

O=c1[nH]c(-c2cccs2)nc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 1.00
KDM4E B2RXH2 5/20 1.00
PKM P14618 1/20 1.00
ALDH1A1 P00352 5/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
HSD17B10 Q99714 2/20 0.62
NPC1 O15118 2/20 0.62
RAB9A P51151 2/20 0.62
TNKS O95271 8/20 0.61
TNKS2 Q9H2K2 7/20 0.61
PARP1 P09874 4/20 0.61
MAPT P10636 2/20 0.59
ALOX15 P16050 1/20 0.59
APOBEC3G Q9HC16 1/20 0.59
ADORA3 P0DMS8 1/20 0.59
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
F2 P00734 1/20 0.56
ERCC1 P07992 1/20 0.56
FEN1 P39748 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11830857 1.00 HPGD (1.00) HPGDKDM4EPKMALDH1A1SMN1; SMN2
SCHEMBL12351809 0.82 HPGD (0.69) HPGDKDM4EPKMALDH1A1HSD17B10
SCHEMBL6695759 0.81 TNKS2 (0.81) HPGDKDM4EPKMALDH1A1HSD17B10
SCHEMBL2249384 0.77 ALDH1A1 (1.00) HPGDKDM4EPKMALDH1A1SMN1; SMN2
SCHEMBL11288258 0.77 HPGD (0.62) HPGDKDM4EPKMALDH1A1HSD17B10
SCHEMBL258433 0.76 TNKS (1.00) HPGDKDM4EALDH1A1HSD17B10NPC1
SCHEMBL6885282 0.76 TNKS (0.93) HPGDKDM4EALDH1A1HSD17B10NPC1
SCHEMBL29592833 0.76 TNKS (1.00) HPGDKDM4EALDH1A1HSD17B10NPC1
SCHEMBL29286005 0.75 HPGD (0.62) HPGDKDM4EPKMALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL31529601 0.75 TNKS (0.96) HPGDKDM4EALDH1A1HSD17B10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010914-A Quinazoline-coumarin compound and preparation method and application thereof 郑州大学 2026-05-12 CN disclosed
CN-119241447-A Method for synthesizing quinazolinone and derivative thereof through photocatalysis three-component serial reaction 淮阴工学院 2025-01-03 CN disclosed
CN-119219562-A Preparation method of quinazolinone derivative 宁夏大学 2024-12-31 CN disclosed
CN-115650924-B Green synthesis method of quinazolinone 山东华泰新材料技术研发有限公司 2024-08-20 CN disclosed
CN-111777564-B Method for synthesizing quinazolinone compound by photocatalytic alcohol oxidation in aqueous phase 许昌学院 2023-07-14 CN disclosed
CN-111875549-B Method for synthesizing quinazolinone compound in aqueous phase through photocatalysis 许昌学院 2023-04-28 CN disclosed