Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.47 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704402 | 0.82 | GRN (0.48) | ALDH1A1TDP1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL19086961 | 0.78 | ALDH1A1 (1.00) | ALDH1A1TDP1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL13692056 | 0.76 | TDP1 (0.47) | ALDH1A1TDP1KMT2ANPSR1MAPK1 | |
| SCHEMBL16388102 | 0.75 | ALDH1A1 (0.62) | ALDH1A1TDP1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL16061522 | 0.74 | ALDH1A1 (0.61) | ALDH1A1TDP1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL30688519 | 0.73 | ALDH1A1 (0.46) | ALDH1A1CACNA1GCACNA1HCACNA1ICYP11B1 | |
| SCHEMBL10053588 | 0.71 | HTT (0.59) | ALDH1A1TDP1CYP11B1CYP11B2MEN1 | |
| SCHEMBL25307087 | 0.70 | CACNA1G (0.46) | ALDH1A1TDP1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL3107233 | 0.70 | CYP19A1 (0.64) | ALDH1A1TDP1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL26251823 | 0.70 | MEN1 (0.51) | ALDH1A1TDP1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230101819-A1 | SMYD Inhibitors | EPIZYME INC (US) | 2023-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230101819-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | ALDH1A1 1611/4885TDP1 1739/4885CACNA1G 4239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.