Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31286290 | 0.80 | CYP19A1 (0.64) | CYP19A1TDP1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL29820311 | 0.80 | CYP19A1 (0.64) | CYP19A1ALDH1A1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL6479494 | 0.80 | CYP19A1 (0.64) | CYP19A1ALDH1A1TDP1CYP11B1CYP11B2 | |
| SCHEMBL16100647 | 0.80 | CYP19A1 (0.64) | CYP19A1TDP1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL29820100 | 0.80 | CYP19A1 (0.69) | CYP19A1ALDH1A1TDP1CYP11B1CYP11B2 | |
| SCHEMBL29471937 | 0.80 | CYP19A1 (0.58) | CYP19A1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3107251 | 0.80 | CYP19A1 (0.58) | CYP19A1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL10194241 | 0.79 | CYP19A1 (0.67) | CYP19A1ALDH1A1CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL155247 | 0.78 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2POLBMAPT | |
| SCHEMBL10053588 | 0.78 | HTT (0.59) | ALDH1A1TDP1CYP11B1CYP11B2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220008887-A1 | Swellable Organically Modified Silica as Nanoreactors | APPALACHIAN STATE UNIVERSITY | 2022-01-13 | — | — | US | disclosed |
| US-20100256357-A1 | HETEROCYCLES USEFUL AS INHIBITORS OF CARBONIC ANHYDRASE | AGOURON PHARMACEUTICALS, INC. | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220008887-A1 | Swellable Organically Modified Silica as Nanoreactors | MSN, SORD, OGA | CYP19A1 3099/4885ALDH1A1 2617/4885TDP1 956/4885 |
| US-20100256357-A1 | HETEROCYCLES USEFUL AS INHIBITORS OF CARBONIC ANHYDRASE | CA2, CA7, CA9 | CYP19A1 1130/4885ALDH1A1 1198/4885TDP1 3993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.