SCHEMBL30365614

SCHEMBL30365614

NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 3/20 0.66
▸ OPRM1 P35372 2/20 0.66
▸ NPBWR1 P48145 17/20 0.63
▸ CCKAR P32238 1/20 0.60
▸ CCKBR P32239 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30365438 0.98 OPRD1 (0.68) OPRD1OPRM1NPBWR1CCKARCCKBR
SCHEMBL30365508 0.96 OPRD1 (0.62) OPRD1OPRM1NPBWR1CCKARCCKBR
SCHEMBL30616037 0.95 OPRD1 (0.66) OPRD1OPRM1NPBWR1CCKARCCKBR
SCHEMBL31731732 0.94 GHSR (0.62) OPRD1OPRM1
SCHEMBL29508662 0.93 GHSR (0.63) OPRD1OPRM1
SCHEMBL29508714 0.91 GHSR (0.64) OPRD1OPRM1
SCHEMBL29616865 0.91 OPRD1 (0.64) OPRD1OPRM1CCKARCCKBR
SCHEMBL30518091 0.91 OPRM1 (0.61) OPRD1OPRM1NPBWR1CCKBR
SCHEMBL31105627 0.91 OPRM1 (0.61) OPRD1OPRM1NPBWR1CCKBR
SCHEMBL29660795 0.90 OPRD1 (0.60) OPRD1OPRM1NPBWR1CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11780880-B2 High-activity memory-improving derivative peptide and use thereof JILIN AGRICULTURAL UNIVERSITY (CN) 2023-10-10 — — US claimed
US-20230104490-A1 High-activity memory-improving derivative peptide and use thereof JILIN AGRICULTURAL UNIVERSITY (CN) 2023-04-06 — — US claimed
US-11780880-B2 High-activity memory-improving derivative peptide and use thereof JILIN AGRICULTURAL UNIVERSITY (CN) 2023-10-10 — — US disclosed
US-20230104490-A1 High-activity memory-improving derivative peptide and use thereof JILIN AGRICULTURAL UNIVERSITY (CN) 2023-04-06 — — US disclosed
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