SCHEMBL30366178

SCHEMBL30366178

CCOc1ccc2c(sc3c(F)c(C4=CCCC4)ccc32)c1F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.32
KDM4E B2RXH2 2/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21847474 1.00 F2RL1 (0.32) F2RL1KDM4EMAPK1HSD17B10ALDH1A1
SCHEMBL18175598 0.81 ALDH1A1 (0.37) F2RL1ALDH1A1
SCHEMBL17189716 0.81 KDM4E (0.42) KDM4EMAPK1HSD17B10ALDH1A1
SCHEMBL16769033 0.78 KCNH2 (0.37) F2RL1KDM4EMAPK1HSD17B10ALDH1A1
SCHEMBL20618754 0.78
SCHEMBL17189714 0.75 KDM4E (0.40) KDM4EMAPK1HSD17B10ALDH1A1
SCHEMBL18911208 0.74 NPSR1 (0.46) F2RL1KDM4EHSD17B10ALDH1A1
SCHEMBL22420470 0.74 MEN1 (0.32)
SCHEMBL19466353 0.74 ALDH1A1 (0.33) ALDH1A1
SCHEMBL17189713 0.74 L3MBTL1 (0.39) KDM4EMAPK1HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110770219-B Derivatives of dibenzofuran and dibenzothiophene 默克专利股份有限公司 2023-04-21 CN disclosed