Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 10/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.51 |
| ▸ | GABRP | O00591 | 6/20 | 0.51 |
| ▸ | GABRD | O14764 | 6/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.51 |
| ▸ | GABRE | P78334 | 6/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30712301 | 0.90 | GABRA1 (0.59) | GABRA2GABRB2GABRA1GABRG2GABRB3 | |
| SCHEMBL2201127 | 0.90 | GABRA1 (0.59) | GABRA2GABRB2GABRA1GABRG2GABRB3 | |
| SCHEMBL30712292 | 0.90 | GABRA1 (0.59) | GABRA2GABRB2GABRA1GABRG2GABRB3 | |
| SCHEMBL4000632 | 0.81 | GABRA1 (0.60) | GABRA2GABRB2GABRA1GABRG2GABRB3 | |
| Trifluoroacetic Acid SCHEMBL5106724 | 0.80 | EGLN1 (0.45) | ALDH1A1CYP1A2L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1658081 | 0.80 | EGLN1 (0.47) | GABRA2GABRB2GABRA1GABRG2GABRB3 | |
| SCHEMBL28680173 | 0.79 | GABRP (0.59) | GABRA2GABRB2GABRA1GABRG2GABRB3 | |
| SCHEMBL27449890 | 0.77 | TSHR (0.60) | GABRA2GABRB2GABRA1GABRG2GABRB3 | |
| SCHEMBL1658084 | 0.76 | EGLN1 (0.41) | GABRA2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL15216308 | 0.75 | GABRA1 (0.46) | GABRA2GABRB2GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903284-B | Fused tricyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2023-05-09 | — | — | CN | disclosed |