SCHEMBL8847375

SCHEMBL8847375

C(OCC1CO1)C1CO1.Clc1cc(Cl)c2ccccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 3/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
GLA P06280 1/20 0.36
CYP1A2 P05177 2/20 0.34
CYP2A6 P11509 1/20 0.34
USP2 O75604 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
DHFR P00374 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
DRD4 P21917 1/20 0.31
MAPK1 P28482 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichlorobenzene SCHEMBL27564197 0.77 TDP1 (0.52) TDP1ALDH1A1TSHRTP53CYP3A4
Naphthalene SCHEMBL1054782 0.77 TDP1 (0.55) TDP1ALDH1A1TSHRTP53CYP3A4
1,3,5-Trichlorobenzene SCHEMBL8847154 0.77 TSHR (0.48) TDP1ALDH1A1TSHRTP53CYP3A4
SCHEMBL5024019 0.77 CYP2A6 (0.54) TDP1ALDH1A1TSHRHIF1ACYP1A2
SCHEMBL30366335 0.77 CYP2A6 (0.54) TDP1ALDH1A1TSHRHIF1ACYP1A2
Chlorobenzene SCHEMBL3159937 0.76 TDP1 (0.55) TDP1ALDH1A1TSHRTP53CYP3A4
SCHEMBL11840470 0.74 TSHR (0.52) TDP1ALDH1A1TSHRTP53CYP3A4
SCHEMBL25543883 0.74 EPHX1 (0.44) TDP1ALDH1A1TSHRTP53CYP3A4
SCHEMBL19612250 0.73 TDP1 (0.46) TDP1ALDH1A1TSHRTP53CYP3A4
SCHEMBL31120479 0.71 ALDH1A1 (0.44) TDP1ALDH1A1TSHRTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605937-B1 Antistatic resin composition DAISO CO LTD (JP) 1997-06-11 EP claimed