SCHEMBL30366377

SCHEMBL30366377

CC(CCC(=O)O)(C(=O)O)N(CC(=O)O)CC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP1A2 P05177 1/20 0.44
THRB P10828 1/20 0.44
NAALAD2 Q9Y3Q0 1/20 0.42
FFAR3 O14843 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
ESR1 P03372 2/20 0.35
CYP3A4 P08684 1/20 0.35
ESR2 Q92731 1/20 0.35
TSHR P16473 6/20 0.33
HIF1A Q16665 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
AKR1B1 P15121 1/20 0.33
HSD17B10 Q99714 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1126526 0.78 ADRA1A (0.48) ALDH1A1FFAR3TSHRHIF1ACYP2D6
SCHEMBL23576186 0.78 NAALAD2 (0.45) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL5159992 0.78 TSHR (0.36) ALDH1A1FFAR3TSHRHIF1ACYP2D6
SCHEMBL31461872 0.78 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL29157393 0.78 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL509992 0.77 NAALAD2 (0.44) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL692324 0.77 NAALAD2 (0.44) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL2027663 0.75 NAALAD2 (0.42) ALDH1A1MEN1KMT2ACYP1A2THRB
Hydrochloric Acid SCHEMBL9775480 0.75 NAALAD2 (0.42) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL8458616 0.75 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ACYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110740757-B Novel PSMA-binding agents and uses thereof 同位素技术慕尼黑公司 2023-04-04 CN disclosed