Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080 | 0.96 | GAA (0.66) | GAAEPHX2CYP3A4CYP2C19L3MBTL1 | |
| Propionamide SCHEMBL1194940 | 0.89 | GAA (0.58) | GAAEPHX2CYP3A4CYP2C19L3MBTL1 | |
| Toluene SCHEMBL10972899 | 0.89 | SMN1; SMN2 (0.64) | GAAEPHX2CYP3A4CYP2C19L3MBTL1 | |
| Oxalic Acid SCHEMBL27880875 | 0.85 | CYP3A4 (0.81) | GAAEPHX2CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL13652538 | 0.85 | LMNA (0.70) | GAAEPHX2CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL15672957 | 0.84 | EPHX2 (0.56) | GAAEPHX2CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL13652537 | 0.82 | ALDH1A1 (0.61) | GAAEPHX2CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL27343037 | 0.82 | MAPT (0.65) | GAAEPHX2CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL16425162 | 0.81 | MTNR1A (0.49) | GAAEPHX2CYP3A4CYP2C19L3MBTL1 | |
| SCHEMBL3087061 | 0.81 | GAA (0.73) | GAAL3MBTL1KMT2AMEN1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996909-A | Process for preparing remifentanil hydrochloride | 麦克法伦史密斯有限公司 | 2023-04-21 | — | — | CN | disclosed |