SCHEMBL30366802

SCHEMBL30366802

FC(F)(F)c1ccc(ONc2ccccc2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.50
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.46
TSHR P16473 1/20 0.46
POLB P06746 1/20 0.45
MAPT P10636 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPK1 P28482 1/20 0.43
GABRA5 P31644 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.42
LMNA P02545 2/20 0.42
LIPE Q05469 1/20 0.41
GAA P10253 1/20 0.41
THRB P10828 1/20 0.40
HTT P42858 1/20 0.40
IDO1 P14902 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60180 0.75 NPC1 (0.59) KMT2ANPC1RAB9ASMN1; SMN2MAPT
SCHEMBL9507549 0.75 MAPK1 (0.64) KMT2ARAB9AHPGDSMN1; SMN2TSHR
SCHEMBL9818990 0.74 ALDH1A1 (0.48) KMT2ANPC1RAB9AHPGDSMN1; SMN2
SCHEMBL8429140 0.72 MRGPRX4 (0.67) KMT2AHPGDSMN1; SMN2TSHRPOLB
SCHEMBL17114620 0.71 NPC1 (0.63) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL8524313 0.71 EPHX2 (0.53) KMT2ANPC1RAB9AHPGDSMN1; SMN2
SCHEMBL706407 0.70 TSHR (0.63) KMT2ANPC1HPGDSMN1; SMN2TSHR
SCHEMBL8989513 0.70 KMT2A (0.56) KMT2ARAB9AHPGDSMN1; SMN2TSHR
SCHEMBL14523045 0.70 KMT2A (0.51) KMT2ARAB9AHPGDSMN1; SMN2TSHR
SCHEMBL706406 0.70 KMT2A (0.51) KMT2ARAB9AHPGDSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894351-B Preparation method of metaflumuron intermediate etherate 江苏天和制药有限公司 2024-07-23 CN claimed
CN-115894351-A Preparation method of acetamiprid intermediate etherate 江苏天和制药有限公司 2023-04-04 CN claimed
CN-115894351-A Preparation method of acetamiprid intermediate etherate 江苏天和制药有限公司 2023-04-04 CN disclosed