Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | LIPE | Q05469 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351938 | 0.91 | MAPT (0.69) | MAPK1KMT2ALIPEMAPTNPSR1 | |
| SCHEMBL4728325 | 0.83 | KDM4E (0.62) | MAPK1KMT2ALIPEMAPTNPSR1 | |
| SCHEMBL21652204 | 0.83 | RAB9A (0.67) | MAPK1KMT2ALIPEMAPTNPSR1 | |
| SCHEMBL30690168 | 0.83 | LMNA (0.63) | MAPK1KMT2ALIPEMAPTNPSR1 | |
| SCHEMBL906222 | 0.83 | LMNA (0.63) | MAPK1KMT2ALIPEMAPTNPSR1 | |
| SCHEMBL921136 | 0.83 | MAPT (0.57) | MAPK1KMT2ALIPEMAPTNPSR1 | |
| SCHEMBL8576331 | 0.83 | MAPT (0.65) | MAPK1KMT2ALIPEMAPTNPSR1 | |
| SCHEMBL11391846 | 0.83 | LIPE (0.67) | MAPK1LIPEMAPTNPSR1HPGD | |
| SCHEMBL9272113 | 0.83 | THRB (0.76) | MAPK1KMT2ALIPEMAPTNPSR1 | |
| SCHEMBL11383589 | 0.83 | LIPE (0.65) | MAPK1KMT2ALIPEMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152328-A | 2-PHENOXY-5-TRIFLUOROMETHYLPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | ISHIHARA SANGYO KAISHA LTD. (JP) | 1979-05-01 | — | — | US | claimed |
| JP-61280476-A | — | — | None | — | — | JP | disclosed |
| US-20240024313-A1 | BIARYL ETHER UREA COMPOUNDS | Jazz Pharmaceuticals Therapeutics, Inc. | 2024-01-25 | — | — | US | disclosed |
| US-20200172518-A1 | SULFONAMIDE-SUBSTITUTED CYANOPYRROLIDINES WITH ACTIVITY AS DUB INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2020-06-04 | — | — | US | disclosed |
| WO-2018210660-A1 | HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES | BASF SE (DE) | 2018-11-22 | — | — | WO | disclosed |
| WO-2018210658-A1 | HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES | BASF SE (DE) | 2018-11-22 | — | — | WO | disclosed |
| WO-2018210661-A1 | HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES | BASF SE (DE) | 2018-11-22 | — | — | WO | disclosed |
| WO-2018210659-A1 | HETEROARYL COMPOUNDS AS AGROCHEMICAL FUNGICIDES | BASF SE (DE) | 2018-11-22 | — | — | WO | disclosed |
| EP-0281103-B1 | PHENOXYCARBOXYLIC ACID COMPOUNDS AND HERBICIDE COMPRISING IT AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1993-06-23 | — | — | EP | disclosed |
| US-4845264-A | PRE- AND POST-EMERGENCE FOR BROAD-LEAVED WEEDS | TEIJIN LIMITED (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0281103-A2 | Phenoxycarboxylic acid compounds and herbicide comprising it as active ingredient | TEIJIN LIMITED (JP) | 1988-09-07 | — | — | EP | disclosed |
| JP-S61280476-A | 2-PHENOXY-5-TRIFLUOROMETHYLPYRIDINE COMPOUND | ISHIHARA SANGYO KAISHA LTD | 1986-12-11 | — | — | JP | disclosed |
| US-4267336-A | BY REACTING A 2-PHENOXYPYRIDINE DERIVATIVE WITH A 4-HYDROXYPHENOXYALKANECARBOXYLIC ACID DERIVATIVE | ISHIHARA SANGYO KAISHA LTD. (JP) | 1981-05-12 | — | — | US | disclosed |
| US-4152328-A | 2-PHENOXY-5-TRIFLUOROMETHYLPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | ISHIHARA SANGYO KAISHA LTD. (JP) | 1979-05-01 | — | — | US | disclosed |
| US-4152328-A | 2-PHENOXY-5-TRIFLUOROMETHYLPYRIDINE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | ISHIHARA SANGYO KAISHA LTD. (JP) | 1979-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172518-A1 | SULFONAMIDE-SUBSTITUTED CYANOPYRROLIDINES WITH ACTIVITY AS DUB INHIBITORS | USP30, USP1, USP39 | MAPK1 2003/4885KMT2A 2752/4885LIPE 3297/4885 |
| US-20240024313-A1 | BIARYL ETHER UREA COMPOUNDS | FAAH, FAAH2, FAH | MAPK1 4121/4885KMT2A 1992/4885LIPE 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.