Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19878143 | 0.83 | VNN1 (0.47) | MAPTKDM4EMAPK1GAATHRB | |
| SCHEMBL19878173 | 0.80 | GAA (0.44) | KMT2ARAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL29628182 | 0.80 | GAA (0.44) | KMT2ARAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL30367508 | 0.80 | LMNA (0.42) | KMT2ARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL13201555 | 0.79 | GAA (0.49) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL26608015 | 0.70 | KMT2A (1.00) | KMT2ARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL30367576 | 0.70 | ROCK1 (0.62) | KMT2ARAB9ANPC1MAPTKDM4E | |
| SCHEMBL346269 | 0.69 | KMT2A (0.67) | KMT2ARAB9ANPC1MAPTKDM4E | |
| SCHEMBL4982448 | 0.67 | MAPT (0.57) | KMT2ARAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL30499529 | 0.67 | KMT2A (0.43) | KMT2ARAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |