Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.42 |
| ▸ | GLP1R | P43220 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30710766 | 0.76 | CYP19A1 (0.49) | CYP19A1TP53ALOX12CA1CA2 | |
| SCHEMBL31258781 | 0.73 | WDR5 (0.41) | CYP19A1TP53GABRA2GABRB2MAPT | |
| SCHEMBL18372519 | 0.71 | CYP19A1 (0.47) | CYP19A1TP53ALOX12CA1CA2 | |
| SCHEMBL16303616 | 0.71 | TP53 (0.51) | CYP19A1TP53ALOX12CA1CA2 | |
| SCHEMBL17362509 | 0.71 | HSD17B10 (0.49) | TP53GLP1RGABRA2GABRB2MAPT | |
| SCHEMBL16983065 | 0.70 | ALDH1A1 (0.44) | TP53CA1CA2MAPTALDH1A1 | |
| SCHEMBL27389813 | 0.69 | WDR5 (0.41) | TP53GABRA2GABRB2MAPTALDH1A1 | |
| SCHEMBL21407529 | 0.68 | TP53 (0.53) | CYP19A1TP53ALOX12CA1CA2 | |
| SCHEMBL27080649 | 0.67 | KMT2A (0.44) | CA1CA2CA9GABRA2GABRB2 | |
| SCHEMBL29267273 | 0.67 | IDO1 (0.42) | TP53GABRA2GABRB2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |