Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.51 |
| ▸ | AXL | P30530 | 9/20 | 0.51 |
| ▸ | MERTK | Q12866 | 8/20 | 0.51 |
| ▸ | TYRO3 | Q06418 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29052490 | 1.00 | MET (0.51) | METAXLMERTKTYRO3 | |
| SCHEMBL30367420 | 0.87 | MERTK (0.50) | METAXLMERTKTYRO3 | |
| SCHEMBL29052485 | 0.87 | MERTK (0.50) | METAXLMERTKTYRO3 | |
| SCHEMBL30367688 | 0.87 | MERTK (0.46) | METAXLMERTKTYRO3 | |
| SCHEMBL29052756 | 0.87 | MERTK (0.46) | METAXLMERTKTYRO3 | |
| SCHEMBL29052459 | 0.86 | TYRO3 (0.55) | AXLMERTKTYRO3 | |
| SCHEMBL30367626 | 0.86 | TYRO3 (0.55) | AXLMERTKTYRO3 | |
| SCHEMBL30367373 | 0.82 | TYRO3 (0.47) | AXLMERTKTYRO3 | |
| SCHEMBL29052440 | 0.82 | TYRO3 (0.51) | MERTKTYRO3 | |
| SCHEMBL30367384 | 0.80 | MAPK1 (0.40) | METAXLMERTKTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |