Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21461009 | 1.00 | CA1 (0.47) | CA1CA2CA9CTSDALDH1A1 | |
| SCHEMBL28709174 | 0.85 | HDAC8 (0.48) | CA1CA9ALDH1A1LCLAT1CTSL | |
| SCHEMBL29599784 | 0.85 | HDAC8 (0.48) | CA1CA9ALDH1A1LCLAT1CTSL | |
| SCHEMBL1850639 | 0.82 | CTSL (0.39) | ALDH1A1P2RX7LCLAT1CTSLKMT2A | |
| SCHEMBL145178 | 0.81 | GAA (0.56) | ALDH1A1LCLAT1KMT2AMEN1GAA | |
| SCHEMBL2646708 | 0.81 | CES2 (0.61) | CA1CA2CA9CTSDALDH1A1 | |
| SCHEMBL2722234 | 0.81 | CA1 (0.50) | CA1CA2CA9CTSDALDH1A1 | |
| SCHEMBL406053 | 0.80 | CA1 (0.58) | CA1CA2CA9CTSDALDH1A1 | |
| SCHEMBL21625558 | 0.79 | CA1 (0.49) | CA1CA2CA9CTSDALDH1A1 | |
| SCHEMBL30015441 | 0.79 | CA1 (0.49) | CA1CA2CA9CTSDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117242072-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-12-15 | — | — | CN | disclosed |
| US-20230174553-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174553-A1 | TYK2 INHIBITORS AND USES THEREOF | TYK2, JAK2, JAK1 | CA1 4860/4885CA2 4083/4885CA9 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.