Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 12/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30368210 | 0.85 | ANO1 (0.65) | ANO1JAK2JAK1TYK2P2RX4 | |
| SCHEMBL30368259 | 0.84 | ANO1 (0.66) | ANO1JAK2JAK1TYK2CSF1R | |
| SCHEMBL30368264 | 0.82 | JAK2 (0.55) | ANO1JAK2JAK1TYK2CSF1R | |
| SCHEMBL30367890 | 0.81 | SMN1; SMN2 (0.57) | ANO1JAK2JAK1TYK2NPC1 | |
| SCHEMBL25370078 | 0.79 | P2RX4 (0.59) | ANO1P2RX4 | |
| SCHEMBL30368345 | 0.79 | JAK2 (0.52) | ANO1JAK2JAK1TYK2NPC1 | |
| SCHEMBL30368445 | 0.79 | NTRK1 (0.51) | ANO1JAK2JAK1TYK2CSF1R | |
| SCHEMBL30368101 | 0.78 | SMN1; SMN2 (0.65) | ANO1JAK2JAK1TYK2P2RX4 | |
| SCHEMBL30368230 | 0.78 | JAK2 (0.62) | ANO1JAK2JAK1TYK2P2RX4 | |
| SCHEMBL30368235 | 0.75 | JAK2 (0.55) | ANO1JAK2JAK1TYK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4172146-A1 | SUBSTITUTED N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY | Bayer Aktiengesellschaft (DE) | 2023-05-03 | — | — | EP | disclosed |