Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29029237 | 0.86 | NTRK1 (0.48) | NTRK1ANO1SMN1; SMN2RORC | |
| SCHEMBL30368259 | 0.84 | ANO1 (0.66) | NTRK1CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL30382576 | 0.81 | NAMPT (0.50) | NTRK1SMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL30368230 | 0.80 | JAK2 (0.62) | ANO1JAK2JAK1TYK2 | |
| SCHEMBL30368170 | 0.79 | ANO1 (0.51) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL30285530 | 0.79 | P2RX4 (0.53) | NTRK1ANO1SMN1; SMN2 | |
| SCHEMBL26186498 | 0.79 | P2RX4 (0.53) | NTRK1ANO1SMN1; SMN2 | |
| SCHEMBL26186528 | 0.78 | P2RX4 (0.50) | NTRK1ANO1SMN1; SMN2 | |
| SCHEMBL30368264 | 0.78 | JAK2 (0.55) | CSF1RPDGFRBKITPDGFRAFLT3 | |
| SCHEMBL2182471 | 0.77 | WNT3A (0.62) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4172146-A1 | SUBSTITUTED N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY | Bayer Aktiengesellschaft (DE) | 2023-05-03 | — | — | EP | disclosed |
| EP-4171744-A1 | USE OF N-PHENYLACETAMIDES HAVING P2X4 RECEPTOR ANTAGONISTIC ACTIVITY FOR TREATING CERTAIN OCULAR DISORDERS | Bayer Aktiengesellschaft (DE) | 2023-05-03 | — | — | EP | disclosed |