Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 19/20 | 0.43 |
| ▸ | RARB | P10826 | 12/20 | 0.43 |
| ▸ | RARG | P13631 | 11/20 | 0.43 |
| ▸ | RXRB | P28702 | 8/20 | 0.43 |
| ▸ | RARA | P10276 | 7/20 | 0.43 |
| ▸ | RXRG | P48443 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065980 | 1.00 | RXRA (0.43) | RXRARARBRARGRXRBRARA | |
| SCHEMBL12418596 | 0.83 | RXRA (0.50) | RXRARARBRARGRXRBRARA | |
| SCHEMBL11122818 | 0.81 | RARB (0.41) | RXRARARBRARGRXRBRARA | |
| SCHEMBL30232111 | 0.81 | RARG (0.41) | RXRARARBRARGRXRBRARA | |
| SCHEMBL8056473 | 0.81 | RARG (0.41) | RXRARARBRARGRXRBRARA | |
| SCHEMBL8807547 | 0.77 | RXRA (0.44) | RXRARARBRARGRXRBRARA | |
| SCHEMBL3298635 | 0.77 | RXRA (0.61) | RXRARARBRARGRXRBRARA | |
| SCHEMBL726366 | 0.77 | RXRA (0.59) | RXRARARBRARGRXRBRARA | |
| SCHEMBL29260311 | 0.75 | POLA1 (0.34) | — | |
| SCHEMBL9859988 | 0.75 | RXRA (0.60) | RXRARARBRARGRXRBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141239-B1 | FRAGRANCE COMPOSITIONS AND USES THEREOF | PROCTER & GAMBLE (US) | 2023-05-10 | — | — | EP | disclosed |