SCHEMBL8056473

SCHEMBL8056473

CC(=O)c1cc2c(cc1C=O)C(C)(C)C(C)CC2(C)C

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RARG P13631 5/20 0.41
RXRA P19793 6/20 0.32
RARB P10826 5/20 0.32
RXRB P28702 4/20 0.32
RXRG P48443 4/20 0.32
RARA P10276 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30232111 1.00 RARG (0.41) RARGRXRARARBRXRBRXRG
SCHEMBL9299399 0.81 RARG (0.52) RARGRXRARARBRXRBRXRG
SCHEMBL10689218 0.81 RARG (0.52) RARGRXRARARBRXRBRXRG
SCHEMBL29357179 0.81 RARG (0.52) RARGRXRARARBRXRBRXRG
SCHEMBL110818 0.81 RARG (0.52) RARGRXRARARBRXRBRXRG
SCHEMBL23633279 0.81 RARG (0.52) RARGRXRARARBRXRBRXRG
SCHEMBL8065980 0.81 RXRA (0.43) RARGRXRARARBRXRBRXRG
SCHEMBL30368657 0.81 RXRA (0.43) RARGRXRARARBRXRBRXRG
SCHEMBL9211089 0.80 RARG (0.47) RARGRXRARARBRXRBRXRG
SCHEMBL9216823 0.80 RARG (0.47) RARGRXRARARBRXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10336966-B2 Fragrance compositions and uses thereof THE PROCTER & GAMBLE COMPANY (US) 2019-07-02 US claimed
US-6147049-A FRAGRANCE COMPOSITION GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2000-11-14 US claimed
EP-1010686-A1 New Tetrahydronaphthalenes Givaudan Roure (International) S.A. (CH) 2000-06-21 EP claimed
EP-1010685-A1 New tetrahydronaphthalenes Givaudan Roure (International) S.A. (CH) 2000-06-21 EP claimed
EP-3103523-B1 ABSORBENT ARTICLE COMPRISING FRAGRANCE COMPOSITION PROCTER & GAMBLE (US) 2025-10-29 EP disclosed
EP-3141239-B1 FRAGRANCE COMPOSITIONS AND USES THEREOF PROCTER & GAMBLE (US) 2023-05-10 EP disclosed
US-20230048533-A1 FRAGRANCE COMPOSITIONS ELC MANAGEMENT LLC 2023-02-16 US disclosed
US-20210393506-A1 FRAGRANCE BLENDS AND METHODS FOR PREPARATION THEREOF JPMORGAN CHASE BANK, N.A. 2021-12-23 US disclosed
EP-3103431-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF The Procter and Gamble Company (US) 2016-12-14 EP disclosed
EP-3103523-A1 ABSORBENT ARTICLE COMPRISING FRAGRANCE COMPOSITION The Procter and Gamble Company (US) 2016-12-14 EP disclosed
US-6147049-A FRAGRANCE COMPOSITION GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2000-11-14 US disclosed
EP-1010686-A1 New Tetrahydronaphthalenes Givaudan Roure (International) S.A. (CH) 2000-06-21 EP disclosed
EP-1010685-A1 New tetrahydronaphthalenes Givaudan Roure (International) S.A. (CH) 2000-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10336966-B2 Fragrance compositions and uses thereof CUTA, DPM1, PLIN5 RARG 1890/4885RXRA 1429/4885RARB 2984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.