Peganole

Peganole

SCHEMBL30368933

OC1c2ccccc2N=C2CCCN21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 1/20 0.50
ACHE P22303 8/20 0.47
BCHE P06276 2/20 0.47
MEN1 O00255 1/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
KMT2A Q03164 1/20 0.46
NOS1 P29475 6/20 0.35
NOS3 P29474 3/20 0.35
NOS2 P35228 3/20 0.35
CACNA1G O43497 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Peganole SCHEMBL4111529 1.00 KLK7 (0.50) KLK7ACHEBCHEMEN1USP2
SCHEMBL9379522 0.81 ACHE (0.44) KLK7ACHEBCHEMEN1USP2
SCHEMBL9381689 0.76 ACHE (0.48) ACHEBCHEMEN1USP2ALDH1A1
SCHEMBL9380285 0.75 ACHE (0.47) ACHEBCHEMEN1USP2ALDH1A1
SCHEMBL9380862 0.75 ACHE (0.47) KLK7ACHEBCHEMEN1USP2
SCHEMBL9385658 0.70 ACHE (0.42) ACHEBCHEMEN1USP2ALDH1A1
SCHEMBL13633898 0.66 NOS1 (0.36) MEN1KMT2ANOS1NOS3NOS2
SCHEMBL9383664 0.65 ACHE (0.45) KLK7ACHEBCHEMEN1USP2
SCHEMBL29416837 0.65 ACHE (1.00) ACHEBCHEMEN1USP2ALDH1A1
SCHEMBL3387188 0.65 ACHE (1.00) ACHEBCHEMEN1USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118488786-A Antimicrobial systems with beta-carboline alkaloids and indole alkaloids and compositions containing them 联合利华知识产权控股有限公司 2024-08-13 CN claimed
CN-118414085-A Antimicrobial systems with beta carboline alkaloids and phenolic acids and compositions containing them 联合利华知识产权控股有限公司 2024-07-30 CN claimed
CN-119968198-A High solubility harmine preparation 莱科奈科特实验室股份公司 2025-05-09 CN disclosed
CN-118453594-A Application of beta-carboline alkaloid in preparation of medicine for treating mitochondrial diseases 温州医科大学 2024-08-09 CN disclosed
CN-115997011-A Adeno-associated virus with engineered capsid 特纳亚治疗股份有限公司 2023-04-21 CN disclosed