Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.79 |
| ▸ | ANPEP | P15144 | 4/20 | 0.79 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.32 |
| ▸ | PEPD | P12955 | 2/20 | 0.32 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14941114 | 1.00 | MMP2 (0.79) | MMP2ANPEPDPP4DPP8DPP9 | |
| SCHEMBL16171927 | 0.88 | MMP2 (1.00) | MMP2ANPEPDPP4DPP8DPP9 | |
| SCHEMBL30476594 | 0.88 | MMP2 (1.00) | MMP2ANPEPDPP4DPP8DPP9 | |
| SCHEMBL29591658 | 0.83 | MMP2 (0.71) | MMP2ANPEPDPP4DPP8DPP9 | |
| SCHEMBL19744399 | 0.83 | MMP2 (0.54) | MMP2ANPEPDPP4DPP8DPP9 | |
| SCHEMBL29260191 | 0.83 | MMP2 (0.54) | MMP2ANPEPDPP4DPP8DPP9 | |
| SCHEMBL18339420 | 0.83 | MMP2 (0.54) | MMP2ANPEPDPP4DPP8DPP9 | |
| SCHEMBL19744398 | 0.83 | MMP2 (0.54) | MMP2ANPEPDPP4DPP8DPP9 | |
| SCHEMBL21682451 | 0.83 | MMP2 (0.54) | MMP2ANPEPDPP4DPP8DPP9 | |
| SCHEMBL13494285 | 0.82 | MMP2 (0.70) | MMP2ANPEPDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157834-A1 | N-(1-CYANO-PYRROLIDIN-3-YL)-5-(3-(TRIFLUOROMETHYL)PHENYL)OXAZOLE-2-CARBOXAMIDE DERIVATIVES AND THE CORRESPONDING OXADIAZOLE DERIVATIVES AS USP30 INHIBITORS FOR THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION | Mission Therapeutics Limited (GB) | 2023-04-05 | — | — | EP | disclosed |