Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28983091 | 1.00 | CYP19A1 (0.47) | CYP19A1ALOX15ALOX12MEN1KMT2A | |
| SCHEMBL30370325 | 1.00 | CYP19A1 (0.47) | CYP19A1ALOX15ALOX12MEN1KMT2A | |
| SCHEMBL31494783 | 1.00 | CYP19A1 (0.47) | CYP19A1ALOX15ALOX12MEN1KMT2A | |
| SCHEMBL28983095 | 1.00 | CYP19A1 (0.47) | CYP19A1ALOX15ALOX12MEN1KMT2A | |
| SCHEMBL29669552 | 0.83 | LMNA (0.33) | CYP19A1ALOX15ALOX12MGLL | |
| SCHEMBL5021772 | 0.82 | KDM1A (0.42) | CYP19A1MEN1KMT2AHTR2CNPC1 | |
| SCHEMBL28983102 | 0.82 | KDM1A (0.42) | CYP19A1MEN1KMT2AHTR2CNPC1 | |
| SCHEMBL30370014 | 0.82 | KDM1A (0.42) | CYP19A1MEN1KMT2AHTR2CNPC1 | |
| SCHEMBL28983100 | 0.82 | KDM1A (0.42) | CYP19A1MEN1KMT2AHTR2CNPC1 | |
| SCHEMBL30370299 | 0.82 | KDM1A (0.42) | CYP19A1MEN1KMT2AHTR2CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115927276-A | Halogen alcohol dehalogenase mutant and application thereof in synthesizing chiral oxazolidinone | 中国科学院天津工业生物技术研究所 | 2023-04-07 | — | — | CN | claimed |