Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 2/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3237564 | 0.88 | TAAR1 (0.64) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL3903656 | 0.87 | MTOR (0.52) | TAAR1IDO1MTORLTA4HMAOB | |
| SCHEMBL7435425 | 0.82 | TAAR1 (0.58) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL30370514 | 0.82 | TAAR1 (0.58) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL4661 | 0.82 | CA1 (0.57) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL29824423 | 0.82 | CA1 (0.57) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL9200966 | 0.82 | TAAR1 (0.60) | TAAR1IDO1ALDH1A1MAOB | |
| SCHEMBL1504972 | 0.80 | CA1 (0.55) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL1504913 | 0.80 | CA1 (0.55) | TAAR1IDO1HTR2AHTR2CHTR2B | |
| SCHEMBL1551304 | 0.78 | LTA4H (0.54) | TAAR1IDO1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |