Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 13/20 | 0.68 |
| ▸ | DRD2 | P14416 | 10/20 | 0.68 |
| ▸ | DRD3 | P35462 | 3/20 | 0.68 |
| ▸ | DRD4 | P21917 | 1/20 | 0.68 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.68 |
| ▸ | HTR7 | P34969 | 14/20 | 0.63 |
| ▸ | HTR2A | P28223 | 13/20 | 0.63 |
| ▸ | HTR6 | P50406 | 9/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25758369 | 1.00 | HTR1A (0.68) | HTR1ADRD2DRD3DRD4ADRA1D | |
| SCHEMBL30375355 | 0.83 | DRD2 (0.53) | HTR1ADRD2DRD3DRD4ADRA1D | |
| SCHEMBL24069102 | 0.83 | DRD2 (0.53) | HTR1ADRD2DRD3DRD4ADRA1D | |
| SCHEMBL25245558 | 0.82 | HTR7 (0.80) | HTR1ADRD2HTR7HTR2AHTR6 | |
| SCHEMBL25758396 | 0.80 | HTR7 (0.73) | HTR1AHTR7HTR2AHTR2C | |
| SCHEMBL13285873 | 0.79 | HTR7 (0.56) | HTR7 | |
| SCHEMBL23648883 | 0.78 | HTR7 (0.56) | HTR1AHTR7HTR2AHTR2C | |
| SCHEMBL23649331 | 0.78 | KMT2A (0.67) | HTR7HTR2A | |
| SCHEMBL30375980 | 0.77 | HTR7 (0.82) | HTR1ADRD2HTR7HTR2AHTR6 | |
| SCHEMBL25758387 | 0.77 | HTR7 (0.82) | HTR1ADRD2HTR7HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | claimed |
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | disclosed |
| EP-4159718-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |